Case Study
How Sella Delivers Scalable Credit Risk Explanations with Prometheux
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Ontologies for Pharma & Life Sciences

From drug discovery to patient access — replace fragmented research pipelines and opaque AI with a unified semantic layer that accelerates decisions and meets regulatory standards by design.

The Problem

Disconnected Research & Clinical Data

Genomic, clinical, trial, and commercial data live in isolated systems. Connecting drug-gene interactions, patient cohorts, and HCP networks requires months of manual integration — by which time the insight window has closed.

Opaque AI with No Regulatory Cover

AI models accelerate discovery, but regulators require traceable, reproducible reasoning. Most pharma AI cannot explain its outputs — creating compliance risk that blocks adoption at the point of submission.

Patient Access Delayed by Data Friction

Drug repurposing, clinical trial recruitment, and patient pathway analysis all rely on multi-hop reasoning across disconnected sources. Without a unified semantic layer, life-saving workflows take years longer than necessary.

The Ontology Advantage

Accelerate R&D Productivity

  • Connect patient, protocol, and outcome data to speed clinical trial analysis and reduce recruitment bottlenecks
  • Link molecular, genomic, and phenotypic data to surface high-confidence drug targets with traceable evidence
  • Aggregate real-world evidence and scientific literature across distributed sources to inform faster R&D decisions
  • Faster drug candidate identification through connected molecular and clinical data reasoning

Optimise Supply Chain & Manufacturing

  • Full batch lineage from raw input to product release — every deviation tracked and auditable automatically
  • Align procurement and production schedules to clinical milestones and evolving market demand signals in real time
  • Monitor and document temperature-sensitive logistics against regulatory standards with continuous ontology-driven oversight
  • Recall readiness: identify and isolate affected batches across the supply chain in minutes, not days

Improve Commercial Effectiveness

  • Personalise HCP outreach based on real-time prescribing patterns, specialty, and territory performance data
  • Coordinate market access, medical, and commercial data across all launch milestones with full cross-functional visibility
  • Track payer decisions and reimbursement changes to adjust field strategies dynamically as conditions evolve
  • HCP engagement programmes grounded in real prescribing and influence data — not demographic approximations

Strengthen Regulatory Compliance

  • Every inference is deterministic and traceable — meeting FDA, EMA, and ICH explainability standards by design
  • Automated audit trails and validation documentation built into every analytical workflow, not added after the fact
  • Submission-ready reporting from a single governed data layer — consistent, reproducible, and inspection-ready
  • No data migration — works on your existing research, clinical, and supply chain infrastructure

Get Started in One Session

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From Our Happy Customers

SD
Senior Director
US Biotech · Rare Disease Space

Prometheux is a Trusted Knowledge and Decision Intelligence platform. Imagine being able to define concepts connected to any source and orchestrate these to solve complex business challenges. In the age of AI and LLMs, Prometheux is a critical tool to ensure decisions are made with proper context, transparency and explainability.

Marco Romei
Marco Romei
Deputy CIO · Banca Sella

Generative AI without ontologies is an engine without a road. Prometheux builds the road.

Anna Fava
Anna Fava
Former Senior Manager, Data & AI · Dompé

Prometheux is more than just technology; it is a catalyst for fact-based decision-making. The ability to query heterogeneous databases through a flexible ontology makes it possible to infer deep knowledge and automate complex tasks, delivering trustworthy insights that far exceed the capabilities of traditional systems.

HR
Head of R&D
Central Bank

With Prometheux, we achieved a speed-up of over 250% on critical tasks involving complex reasoning over knowledge graphs with hundreds of millions of nodes and billions of edges. In the financial domain, where timeliness and analytical depth are both essential, this level of performance improvement significantly enhances our ability to extract insights, manage risk, and support data-driven decision-making at scale.

Massimiliano Malin
Massimiliano Malin
Head of Credit Risk · Banca Sella

Prometheux enabled us to build a system that can access our databases, process all the client’s historical variables, and provide an intelligent, understandable explanation autonomously.

SD
Senior Director
US Biotech · Rare Disease Space

Prometheux is a Trusted Knowledge and Decision Intelligence platform. Imagine being able to define concepts connected to any source and orchestrate these to solve complex business challenges. In the age of AI and LLMs, Prometheux is a critical tool to ensure decisions are made with proper context, transparency and explainability.

Marco Romei
Marco Romei
Deputy CIO · Banca Sella

Generative AI without ontologies is an engine without a road. Prometheux builds the road.

Anna Fava
Anna Fava
Former Senior Manager, Data & AI · Dompé

Prometheux is more than just technology; it is a catalyst for fact-based decision-making. The ability to query heterogeneous databases through a flexible ontology makes it possible to infer deep knowledge and automate complex tasks, delivering trustworthy insights that far exceed the capabilities of traditional systems.

HR
Head of R&D
Central Bank

With Prometheux, we achieved a speed-up of over 250% on critical tasks involving complex reasoning over knowledge graphs with hundreds of millions of nodes and billions of edges. In the financial domain, where timeliness and analytical depth are both essential, this level of performance improvement significantly enhances our ability to extract insights, manage risk, and support data-driven decision-making at scale.

Massimiliano Malin
Massimiliano Malin
Head of Credit Risk · Banca Sella

Prometheux enabled us to build a system that can access our databases, process all the client’s historical variables, and provide an intelligent, understandable explanation autonomously.

Why Prometheux?

Ontology Native

The only data engine that makes ontologies operational

Zero Lock-In

Works across your existing infra. No migrations. No GraphDBs

Ridiculously Faster

Exponential speed gains, minutes not months

Fully Explainable

Deterministic, auditable, compliance-ready

Agent Ready

Purpose-built for deterministic agentic workflows you can trust

Full Control

Transparent by design

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Power Up Your Stack in 1 Click.

Deploy on your existing infrastructure. Run workloads natively on your existing compute, entirely within your environment with our native integrations.

Resource Center

Perspectives on our customers, future of data, AI, and ontologies.

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Case Study
How Sella Delivers Scalable Credit Risk Explanations with Prometheux

Transforming credit risk analysis from 17 minutes to 5 seconds.

READ MORE

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